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Clonidine transdermal is used alone or together with other medicines to treat high blood pressure (hypertension). Clonidine transdermal is used alone or together with other medicines to treat high blood pressure (hypertension). The Catapres-TTS patch is square and the cover patch is round. The Catapres-TTS patch is square and the cover patch is round. It is also called an antihypertensive agent Catapres‑TTS ® (clonidine transdermal system) is a transdermal system providing continuous systemic delivery of clonidine for 7 days at an approximately constant rate. It is also called an antihypertensive agent Catapres‑TTS ® (clonidine transdermal system) is a transdermal system providing continuous systemic delivery of clonidine for 7 days at an approximately constant rate. Catapres-TTS is a transdermal system providing continuous systemic delivery of clonidine for 7. Catapres-TTS is a transdermal system providing continuous systemic delivery of clonidine for 7. 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