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Both Garrett and Winkler admitted in court that they were drunk and had taken depressant drugs; the court heard they had each taken equal amounts of alcohol and drugs that night. Clonidine is by no means a “magic bullet” because it doesn’t eliminate all of your opiate withdrawal symptoms. Clonidine is by no means a “magic bullet” because it doesn’t eliminate all of your opiate withdrawal symptoms. The effects of clonidine were especially noticeable with respect to tremor, sweating, elevated systolic blood pressure, tension. The effects of clonidine were especially noticeable with respect to tremor, sweating, elevated systolic blood pressure, tension. It is frequently prescribed to help with the symptoms of catapres withdrawal symptoms Opioid withdrawal. It is frequently prescribed to help with the symptoms of Opioid withdrawal. 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